Originally posted by bonehead
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No traditional handgun is going to have an explosive wound channel like a 5.56mm. They are all big, slow, solid pieces of metal. When you go slow, size matters greatly, which is why in black powder days, the calibers were enormous compared to what we have today. And .45 beats .40, it's basic math.
As far as combat performance, I'd have to give the nod to the .45ACP, which has been killing people quite easily since WW1.
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